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28岁的佐仓明日香职业是一名自由撰稿人。某天她醒来后发现自己躺在了一间白色屋子的床上。原来是一所精神病院的隔离病房，而这里只收女病人。 明日香感觉自己失去了记忆，她完全不知道自己是如何来到这里的。截稿日期将至了，她却没有院方及男友作家铁雄的同意不得出院。 她只好在这个地方继续生活。她认识了患有厌食症的美纪，得了暴食症的西野，虽然刚开始觉得她们都是怪怪的，但明日香还是跟她们成为了朋友。 铁雄派人探望明日香，一时受不了刺激的明日香麻疹发作。即使这样，明日香还是成功对付了医院护士一往的冷酷无情。就在一切仿佛都将要好起来之际，美纪的一个天大秘密，唤醒了明日香的记忆……。女主幼时被母遗弃，幸得瘸腿男主相救并养大，后成明星，亲妈认亲并任其经纪人。女主患肾衰竭需巨资治疗，亲妈为谋利隐瞒，养父欲告知却被亲妈诬陷，致女主误解养父。最终女主病发，养父捐肾救她，女主方知亲妈阴谋。。* Based on the manga by Inoue Noriyoshi, which has also had a SNES game spin-off. Natsume Kiroemon is the 45th leader of the Natsume family to inherit the Kouryuu no Mimi, a tool which gives its bearer easy access to wealth and women. As a result of his father's death, he leaves the Italian monastery where he had been training and to rightfully take on the name Natsume Kiroemon...。